Dirty Genes™ - MTHFR Supplements
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
If you have an MTHFR gene SNP, you need supplementation that is bioavailable and doesn’t slow down your methylation processes. MTHFR (short for methylenetetrahydrofolate reductase) produces an enzyme that helps regulate how well your DNA methylation cycle works. Polymorphisms mean that MTHFR less efficiently converts folic acid (vitamin B9) and vitamin B12 to active forms.
An impaired MTHFR gene can also lead to high homocysteine levels, detoxification challenges, and an increased risk for other problems.
For optimal health, you need bioavailable, methylated nutrients like methylcobalamin (methyl-B12), L-5-MTHF (methylfolate), SAMe, creatine, phosphatidylcholine, and more.
These work to support your body’s methylation processes by reducing the effort needed to activate them.
Your MTHFR gene mutation doesn’t have to confuse you. Get started with MTHFR supplements today. Try Seeking Health’s popular Optimal Multivitamin for comprehensive nutrient support. Or get HomocysteX Plus, which helps to support normal homocysteine conversion. B Complex Plus is a great way to support a healthy MTHFR enzyme.
Not sure where to start with a multivitamin? Use this chart to compare products.

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Support a healthy stress response, thyroid and adrenal function, and feelings of calm with Ashwagandha.†
Ashwagandha—A powerful adaptogen formula that is vegan-friendly with over 400 mg of ashwagandha root extract to support feelings of calm and stress resilience in each capsule.†
Ashwagandha
4.9Rated 4.9 out of 5 stars131 ReviewsFrom $25Key Benefits and Actions† High-quality ashwagandha root extract Powerful stress support for life’s everyday stressors Supports a healthy stress ...
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Foster healthy energy production and mood with methyl-free B Complex MF.†
B Complex MF—A potent B vitamin complex containing the 8 essential B vitamins, featuring non-methylated B12 and folate in the forms of hydroxocobalamin and folinic acid.†
B Complex MF
4.5Rated 4.5 out of 5 stars86 ReviewsFrom $30Key Benefits and Actions† Methyl-free vitamin B complex Supports healthy energy production Supports a healthy mood Who Needs B Complex MF Have...
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Support normal hormone balance, a balanced mood, and healthy energy production with B Complex Plus.†
B Complex Plus—A potent vitamin B complex supplement that provides active forms of the 8 essential B vitamins plus choline for additional methylation support.†
Best SellerB Complex Plus
4.9Rated 4.9 out of 5 stars381 ReviewsFrom $30Key Benefits and Actions† Healthy energy production support Supports normal hormone balance and mood Supports healthy methylation and homocystei...
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Support healthy liver metabolism of estrogens, detoxification, and elimination with DIM+13C.†
DIM+I3C—A targeted formula that supports healthy estrogen metabolism and a healthy oxidative stress response associated with xenoestrogen exposure.†
DIM + I3C
4.8Rated 4.8 out of 5 stars134 ReviewsFrom $43Key Benefits and Actions† Supports healthy liver metabolism of estrogens Supports detoxification and elimination Supports healthy inflammatory r...
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Uncover the hidden clues your body has been trying to tell you and unlock the secret of turning genes “on” or “off” for wellness with national, best-selling “Dirty Genes” by Dr. Ben Lynch!
Dirty Genes—Dr. Lynch shows you how to identify and optimize both types of dirty genes by cleaning them up with targeted and personalized plans to ultimately rewire your genetic destiny.
Best SellerDirty Genes by Dr. Ben Lynch
4.8Rated 4.8 out of 5 stars67 ReviewsFrom $20Instant National Bestseller After suffering for years with unexplainable health issues, Dr. Ben Lynch discovered the root cause—“dirty” genes. Gene...
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Get your daily dose of highly-concentrated omega-3s for cardiovascular and heart health support with Fish Oil.†
Fish Oil—Includes omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) that support healthy joint function, normal body weight, normal inflammatory response, and healthy blood pressure.†
Fish Oil
5.0Rated 5.0 out of 5 stars91 ReviewsFrom $40Key Benefits and Actions† Burp-free, taste-free and easy to swallow 400 mg of DHA + 400 mg of EPA as triglycerides per softgel Wild caught...
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Support healthy methylation and homocysteine levels with a methyl-free Folinic Acid Lozenge.†
Folinic Acid Lozenge—Contains a potent dose of 1,360 mcg DFE (800 mcg) of methyl-free folate as folinic acid in a tasty, well-digested form for those sensitive to methylated nutrients.†
Folinic Acid Lozenge
4.9Rated 4.9 out of 5 stars154 ReviewsFrom $20Key Benefits and Actions† Methyl-free folate in a tasty, well-digested lozenge Supports healthy methylation and homocysteine levels Supports hea...
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Foster healthy bile production and bile flow—especially if you’ve had your gallbladder removed—with Gallbladder Nutrients.†
Gallbladder Nutrients—a powerful herbal formula that supports your liver’s bile production and promotes healthy bile flow from your gallbladder into the small intestine.†
Gallbladder Nutrients (Soon Bile Nutrients)
4.6Rated 4.6 out of 5 stars95 ReviewsFrom $40Key Benefits and Actions† Supports healthy bowel movements Supports healthy bile production and bile flow Useful for those with, or without, a g...
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Support healthy detoxification and immune system functioning with easy-to-swallow Glutathione Plus!†
Glutathione Plus—A unique formula with EmothionTM S-Acetyl-L-Glutathione and LifePQQTM for lung, skin, eye, and immune system support, all in a small taste- and smell-free capsule!†
Best SellerGlutathione Plus
4.9Rated 4.9 out of 5 stars128 ReviewsFrom $65Key Benefits and Actions† Supports healthy lungs, skin, eyes and immune system Triple glutathione protection due to unique formulation Easy to s...
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Get the nutrients you need to support a healthy seasonal histamine response with Histamine Nutrients!†
Histamine Nutrients—Provides the nutrients needed to support healthy histamine breakdown, including DAOgest®, zinc, riboflavin, copper, and SAMe, to experience healthy histamine levels.†
Best SellerNew NameHistamine Nutrients - Formerly Histamine Block Plus
4.8Rated 4.8 out of 5 stars234 ReviewsFrom $65Key Benefits and Actions† Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist...
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Target healthy immune system support and healthy inflammatory responses with HistaminX!†
HistaminX—Specially formulated for immune health and seasonal comfort, featuring herbal and plant-derived compounds that synergistically support healthy inflammatory responses.†
HistaminX
4.7Rated 4.7 out of 5 stars161 ReviewsFrom $45Key Benefits and Actions† Healthy immune system support Support for healthy lungs, nose, and airway Supports healthy inflammatory responses Who...
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Keep your homocysteine levels in check with the unique formula found in Homocysteine Nutrients!†
Homocysteine Nutrients—Provides the 5 nutrients your body requires for optimal methylation, including folate, methylcobalamin, and adenosylcobalamin, to support normal homocysteine breakdown for heart health support.†
Best SellerHomocysteine Nutrients
4.9Rated 4.9 out of 5 stars243 ReviewsFrom $35Key Benefits and Actions† Supports healthy methylation & homocysteine levels Powerful heart health support Supports healthy cognition & ...
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Start your kids’ day off right with great-tasting and sugar-free Kids Multivitamin Chewable!
Kids Multivitamin Chewable—A comprehensive kids’ multivitamin and multimineral that supports their growth, genes, and important pathways in a tasty, kid-approved chewable.†
Kids Multivitamin Chewable
4.7Rated 4.7 out of 5 stars16 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports kids from 1 year old and up Comprehensive kid’s multivitamin and multimineral Who Needs Kids...
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Start your kids’ day off right with the bioavailable nutrients they need to keep going with Kids Multivitamin Chewable MF!†
Kids Multivitamin Chewable MF—A comprehensive multivitamin and multimineral with methyl-sensitive kids in mind in a great-tasting, kid-approved, and sugar-free chewable.†
Kids Multivitamin Chewable MF
4.6Rated 4.6 out of 5 stars7 ReviewsFrom $30Great-tasting, kid-approved and sugar free Supports methyl-sensitive kids from 1 year old and up Comprehensive kid’s multivitamin and multimin...
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Support healthy methylation, MTHFR, and homocysteine levels with bioavailable L-Methylfolate!†
L-Methylfolate—A superior form of L-methylfolate that readily donates its methyl groups, aids the conversion of the amino acid homocysteine into methionine, and supports your entire methylation cycle.†
L-Methylfolate
4.8Rated 4.8 out of 5 stars89 ReviewsFrom $20Key Benefits and Actions† Powerful methylation, MTHFR, and homocysteine support Supports healthy cognition and mood Healthy genetic expression s...
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Supports healthy aging, detoxification, immune system, and physical activity with Liposomal Glutathione Plus!†
Liposomal Glutathione Plus—A powerful antioxidant support formula with a liposomal delivery that enhances absorption of the reduced, active form of glutathione and other key nutrients that support glutathione recycling and function.†
Best SellerLiposomal Glutathione Plus
4.7Rated 4.7 out of 5 stars364 ReviewsFrom $50Key Benefits and Actions† Powerful liposomal glutathione plus nutrients for recycling and utilization Reduced form supports optimal antioxidant ...
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Help support your hard-working liver to aid in healthy detoxification, glutathione production, and cell function with Liver Nutrients!†
Liver Nutrients—An all-in-one liver-support dietary supplement with a synergistic blend of nutrients and herbs supports the healthy metabolism of toxins and hormones in the liver and promotes normal glutathione production and liver cell regeneration.†
Best SellerLiver Nutrients
4.9Rated 4.9 out of 5 stars315 ReviewsFrom $24Key Benefits and Actions† Phase 2 liver detoxification support Glutathione production support Liver cell function support Who Needs Liver Nutr...
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Best Seller
Methyl B12 with L-Methylfolate
4.9Rated 4.9 out of 5 stars679 ReviewsFrom $25Key Benefits and Actions† Active, methylated folate and B12 in a well-absorbed lozenge Potent methylation, homocysteine, and MTHFR support Suppo...
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Best Seller
Multivitamin One
4.8Rated 4.8 out of 5 stars321 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring bioavailable nutrients Methyl B12 and methylfolate support optimal methylation Powerf...
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Multivitamin One MF
4.9Rated 4.9 out of 5 stars239 ReviewsFrom $35Key Benefits and Actions† One-a-day multivitamin featuring methyl-free B12 and folate Methyl-free support for those sensitive to methylated nutr...
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Best SellerImproved
Optimal Electrolyte
4.5Rated 4.5 out of 5 stars1,305 ReviewsFrom $38Supports healthy muscle contraction and relaxation Supports healthy heart rhythm and contraction Hydration Blend with PeakATP ®, HydroPrime ®, Hi...
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Optimal Focus
4.6Rated 4.6 out of 5 stars86 ReviewsFrom $70Key Benefits and Actions† Supports healthy memory Cognitive function support such as clarity, focus, and learning Stimulant-Free support for nor...
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Best Seller
Optimal Liposomal Glutathione
4.7Rated 4.7 out of 5 stars379 ReviewsFrom $50Key Benefits and Actions† Powerful, well-absorbed, liposomal glutathione Reduced form promotes optimal antioxidant activity Supports healthy agi...
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Best Seller
Optimal Man™
4.8Rated 4.8 out of 5 stars100 ReviewsFrom $65Key Benefits and Actions† Supports men’s health and male fertility Supports healthy testosterone levels Supports healthy cognition, energy, and ...
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